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Symbol
Name
ID

Sh3kbp1
SH3-domain kinase binding protein 1
MGI:1889583

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgG2 level	Decreased circulating IgG4 level	Decreased circulating total IgM	Recurrent sinusitis	Recurrent otitis media	Recurrent bacterial infections	Recurrent respiratory infections
Disease(s) Associated with SH3KBP1
immunodeficiency 61

Mouse Phenotypes		immune system phenotype	decreased immature B cell number	decreased transitional stage T2 B cell number	decreased transitional stage T3 B cell number	abnormal lymphocyte cell number	decreased B-1a cell number	decreased follicular B cell number	decreased B cell number	abnormal B cell physiology	abnormal humoral immune response
Availability	Mouse Genotype
	Sh3kbp1^tm1Kuro/Sh3kbp1^tm1Kuro Cd79a^tm1(cre)Reth/Cd79a⁺ (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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